B12 Deficiency

Symptoms and normal levels.

B12 Deficiency: glass vial filled with deep red liquid
Image generated with AI.

For serum B12, below 200 pg/mL is deficiency and 200–300 pg/mL is borderline. Convert: pg/mL × 0.738 = pmol/L.

Risk groups: vegan diet, metformin and acid-reducing drugs, older age, pernicious anemia.
Statuspg/mLpmol/L
Deficiency<200<148
Borderline (confirm with MMA)200–300148–221
Sufficient≥300≥221
Sources
  • NIH Office of Dietary Supplements — Vitamin B12
  • British Society for Haematology — cobalamin and folate guideline (2014)

General information only; not diagnosis or treatment. Review your results with your clinician.